4,5-Dichloro-2H-1,3-oxazine-2,6(3H)-dione
نویسندگان
چکیده
In the title compound, C(4)HCl(2)NO(3), the essentially planar (maximum deviation = 0.023 Å for the ring O atom) mol-ecules form N-H⋯O hydrogen bonds between mol-ecules lying about inversion centers, forming eight-membered rings with an R(2) (2)(8) motif in graph-set notation.
منابع مشابه
4-Methyl-2H-1,3-oxazine-2,6(3H)-dione
In the title compound, C(5)H(5)NO(3), the planar (maximum deviation = 0.075 Å for the ring O atom) mol-ecules form N-H⋯O hydrogen bonds in a zigzag chain (C-O⋯N bond angle ≃ 140°) between glide-related mol-ecules.
متن کامل4-Bromo-2H-1,3-oxazine-2,6(3H)-dione
The title compound, C(4)H(2)BrNO(3), is one of a series of three substituted oxauracils prepared as precursors in the preparation of 1-aza-1,3-butadienes. Although each structure has identical potential for N-H⋯O inter-molecular hydrogen bonds, each forms a distinctive inter-molecular network. In the title compound, there are two independent mol-ecules in the asymmetric unit, with a non-crystal...
متن کامل7-(1,3-Dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6(1H,3H)-dione trichloroacetic acid solvate
In the title compound, C(11)H(14)N(4)O(4)·C(2)HCl(3)O(2), the dioxolane ring adopts an envelope conformation. Doxophylline [7-(1,3-dioxolan-2-yl-meth-yl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione] and trichloro-acetic acid mol-ecules are linked by O-H⋯N and C-H⋯O hydrogen bonds.
متن کاملIsolation and Characterization of Impurities Present in 8-Chlorotheophylline
A simple isocratic reversed phase high performance liquid chromatography was used to separate three impurities present in the sample of 8-chlorotheophylline. LC-MS was used for the characterization of impurities. Based on mass spectral data, the structures of these impurities were characterized as 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (impurity I), 3,7-dihydro-1,3,7-trimethyl-1H-purine-2...
متن کاملImpact of aromatic substitution on the anticonvulsant activity of new N-(4-arylpiperazin-1-yl)-alkyl-2-azaspiro[4,5]decane-1,3-dione derivatives.
A series of N-[(4-arylpiperazin-1-yl)-alkyl]-2-azaspiro[4.5]decane-1,3-dione derivatives were synthesized and evaluated for their anticonvulsant and neurotoxic properties. The main modifications to that series of compounds consisted in the introduction of an aromatic area to the cyclohexane ring as a flexible fragment with conformational freedom (1a-h), or as a rigidified skeleton (2a-h). Excep...
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عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009